We have created this web page in order to let as many people know about the High Intensity Focus Ultrasound (HIFU) technology used in the Sonablate® system for patients with localized prostate cancer. Seventeen years have already passed by since our first treatment in January 1999. Since then, the procedure has been carried out on 1,468 patients with an excellent record. We sincerely hope that this home page will provide you with useful information that allows you to make the best choice for your own prostate care.

High-intensity Focused Ultrasound (HIFU) for Localized Prostate Cancer

HIFU delivers intense ultrasound energy, with consequent heat destruction of the prostate at a specific focal distance from the transrectal probe without damage to the intervening tissue and skin. I describe here the HIFU effect, morbidity and cost for a localized prostate cancer treatment. Please read it carefully and sign at the bottom to indicate your understanding and agreement to the HIFU therapy.

Candidate for HIFU

Neoadjuvant hormonal therapy for 2-3 months before HIFU or transurethral resection of the prostate (TURP) in just before HIFU is needed in patients whose prostate volume showed more than 40cc to reduce volume of the prostate. In addition, pre TURP should be needed in patients whose prostate contains large calcifications more than 1cm diameter. And, I recommend that the patient should be stay in our hospital for 1 week in that case.

Clinical Outcome

We have performed HIFU treatments in 1,468 patients with localized prostate cancer for the past 17 years.

We can predict the biochemical disease-free rates (success rates) at 5 years depending on their clinical stage, Gleason score and pretreatment serum PSA levels (D’Amico’s classification system) that were treated with latest version of Sonablate 500 TCM in 414 patients are as follows:

Postoperative Course

At present, most of the patients from foreign countries were treated for 5-6 nights stay. In general, we do HIFU in spinal or general anesthesia, and it may well take up to 90 minutes in average for treating 30cc volume of the prostate. A channeling transurethral resection of the prostate (TURP)and bilateral vasectomy are sometimes added in just after the HIFU to prevent post HIFU urinary retention, urethral stricture and acute epididymitis. A 14-16 French sized balloon catheter is indwelled after the HIFU treatment. Self-catheterization is recommended if patients do not want to place a balloon catheter after HIFU.

Postoperative Complications

Generally, most patients have some urge to void more frequently for 6-8 weeks.

No complications were noted other than the above.

Repeat HIFU

Among 1,468 patients, 255 (17.4%) patients were treated with twice, 55 (3.7%) patients with three times, 4 (0.3%) patients with four times, and 2 (0.1%) patients with 5 times.

Medical charges

Generally, 15,000 US$ was charged which includes all of the HIFU therapy, pre and postoperative examinations, and room charges while you are staying in our hospital. Your travel and lodging expenses in hotels are separate.

The change of the agreement

Your signature to this agreement signifies that you have been informed and understand the treatment process and the potential risks to this treatment. If for any reason, you decide to cancel or postpone the therapy, you may do so without penalty.
Please do not hesitate to ask me if you have any questions or concerns about the treatment.

Toyoaki Uchida, M.D.,Ph.D.

Hachioji Urology Clinic 3-6-7 Koyasucho, Hachioji, Tokyo192-0904, Japan
Phone +81-42-649-1528
Mail toyoaki2569uchida@vesta.ocn.ne.jp
Home page http://hachioji-hinyokika.com
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Revision 40: May 20, 2016